Gene Therapy in Oral Cancer: A Review
Published: June 1, 2013 | DOI: https://doi.org/10.7860/JCDR/2013/.3071
M. Sathish Kumar, K.M.K. Masthan, N. Aravindha Babu, Kailash Chandra Dash
1. Professor and Head of the Department, Department of Oral
Pathology and Microbiology, Karpaga Vinayaga Institute of
Dental Science, Chennai, Tamil Nadu, India.
2. Professor and Head of the Department, Department of Oral
Pathology and Microbiology, Sree Balaji Dental College &
Hospital, Bharath University, Chennai, Tamil Nadu,India.
3. Associate Professor, Department of Oral Pathology and
Microbiology, Sree Balaji Dental College & Hospital, Bharath
University, Chennai, Tamil Nadu, India.
4. Post Graduate Student. Department of Oral Pathology and
Microbiology, Sree Balaji Dental College & Hospital, Bharath
University, Chennai, Tamil Nadu, India.
Correspondence
Dr. Kailash Chandra Dash,
Post graduate student, Department of Oral Pathology and
Microbiology, Sree Balaji Dental College & Hospital, Bharath
University, Chennai-600100, Tamil Nadu, India.
Phone: +919789914796/+919444238645
E-mail: dash.rajaji.kailash@gmail.com
Gene therapy is the use of DNA as an agent to treat disease. Gene therapy aims at the insertion of a functional gene into the cells of a patient for the correction of an inborn error of metabolism, to alter or repair an acquired genetic abnormality, and to provide new function to the cell. Many experiments have been done with respect to its application in various diseases.Today, most of the gene therapy studies are aimed at cancer and hereditary diseases which are linked to genetic defects. Cancer usually occurs due to the production of multiple mutations in a single cell which cause it to proliferate out of control. Several methods such as surgery, radiation therapy and chemotherapy have been used widely to treat cancers. But, the cancer patients who are not helped by these therapies can be treated by gene therapy. The purpose of this article is to review the use and purpose of gene therapy in oral cancer.
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